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PLAQUENIL (HYDROXYCHLOROQUINE SULFATE) TABLETS: MEDICATION GUIDE - BEFORE TAKING

What you need to know before you begin taking Plaquenil?

  • Do not take Plaquenil tablets if you are allergic to hydroxychloroquine sulfate, to any of the other ingredients of this medication or any similar drugs such as chloroquine.
  • If you are taking digoxin (a medicine used to treat heart disease) or drugs for diabetes, their dose may need to be reduced.
  • Cases of weakening of the heart muscle, resulting in heart failure and in some cases in death, have been reported in patients treated with Plaquenil. Talk to your doctor if you have symptoms such as breathlessness, swelling of the legs, irregular heart beat or fatigue and dizziness.
  • Plaquenil (Hydroxychloroquine) crosses the placenta (the organ that allows the mother's oxygen and nutrients to pass to the unborn baby); you should tell your doctor if you are pregnant or planning to get pregnant.
  • This drug passes to breast milk; you should tell your doctor, pharmacist, or other healthcare professional if you are breast feeding.
  • Do not take Plaquenil if you have retinopathy (eye problem affecting the retina). Plaquenil (Hydroxychloroquine) tablets may cause irreversible damage to the retina (the back of the eye where vision is created). You are required to have an eye exam before taking this medicine, then a follow-up as often as needed while taking Plaquenil. You should contact your doctor immediately if you experience any of the following visual problems: blurred vision, seeing halos around lights, especially at night, seeing light flashes and streaks, night blindness, visual field loss, change in eye colour (eye pigmentation), difficulty focusing eye, difficulty reading (skipped words).
  • Talk to your healthcare provider if you have been prescribed both Plaquenil and tamoxifen (a medicine used to treat breast cancer). Both Plaquenil (Hydroxychloroquine Sulfate) and tamoxifen can individually induce retinal damage (damage to the back of the eye), and taking both drugs at the same time can increase your risk of retinal damage.
  • If you experience blurred vision when taking Plaquenil, do not drive or participate in activities requiring alertness.
  • This medication can cause hypoglycemia (low blood sugar); sometimes, hypoglycemia may be severe life-threatening, with loss of consciousness or requiring hospitalization. Talk to your doctor if you have symptoms such as sweating, shakiness, weakness, dizziness, fast heartbeat.
  • Tell your doctor if you have/are:

    - liver or kidney disease
    - blood disease, including a rare blood disease called porphyria
    - nervous system disease
    - a skin disease called psoriasis
    - a genetic condition known as "glucose-6-phosphate dehydrogenase deficiency"
    - allergic to chloroquine

  • Consult your doctor if you suddenly experience fainting spell while using Plaquenil. This medication is known to prolong the QT interval (heart rhythm condition that can potentially cause fast, irregular heartbeats).
  • This medication should only be used by the person for whom it is prescribed.
  • Protect your skin from the sun with appropriate clothing and sunscreen cream with a minimum SPF 30 rating when going outdoors.

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